Skip to Content
MilliporeSigma
All Photos(1)

Documents

S1013

Sigma-Aldrich

(−)-Scopolamine hydrochloride

≥90% (HPLC), powder

Synonym(s):

Hyoscine hydrochloride, Scopine tropate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H21NO4 · HCl
CAS Number:
55-16-3
Molecular Weight:
339.81
Beilstein/REAXYS Number:
4168778
EC Number:
200-225-6
MDL number:
MFCD00058096
UNSPSC Code:
12352200
PubChem Substance ID:
24899457

assay

≥90% (HPLC)

form

powder

optical activity

[α]25/D ~−27°, c = 1 in H2O(lit.)

color

white

solubility

H2O: 50 mg/mL

SMILES string

Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

InChI key

KXPXJGYSEPEXMF-MOUKNHLCSA-N

Gene Information

human ... CHRM1(1128)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Caution

The powder is stable at least four years stored at room temperature.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

170.6 °F - closed cup

flash_point_c

77 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Stacey J Sukoff Rizzo et al.
Current protocols in mouse biology, 8(2), e45-e45 (2018-06-21)
The relationship between chronological age (lifespan) and biological age (healthspan) varies amongst individuals. Understanding the normal trajectory and characteristic traits of aging mice throughout their lifespan is important for selecting the most reliable and reproducible measures to test hypotheses. The
Sunjoo Joo et al.
Nature communications, 13(1), 1133-1133 (2022-03-05)
Most sexual organisms inherit organelles from one parent, commonly by excluding organelles from the smaller gametes. However, post-mating elimination of organelles derived from one gamete ensures uniparental inheritance, where the underlying mechanisms to distinguish organelles by their origin remain obscure.
X Bian et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 21(9), 969-977 (2009-04-21)
Neuromuscular transmission is crucial for normal gut motility but little is known about its postnatal maturation. This study investigated excitatory/inhibitory neuromuscular transmission in vitro using ileal nerve-muscle preparations made from neonatal (< or =48 h postnatal) and adult ( approximately
Fang-Fang Chen et al.
Oncoimmunology, 9(1), 1831153-1831153 (2020-10-29)
Therapeutic monoclonal antibodies against the PD-L1/PD-1 (programmed death ligand-1/programmed cell death protein-1) axis have achieved great successes in cancer treatments, but the development of small-molecule immunomodulators of the pathway has lagged far behind. We established a cellular coculture assay with
Narayana Krishna Yelleswarapu et al.
Neurogastroenterology and motility, 34(12), e14439-e14439 (2022-12-03)
Alterations in gastrointestinal (GI) function and the gut-brain axis are associated with progression and pathology of Alzheimer's Disease (AD). Studies in AD animal models show that changes in the gut microbiome and inflammatory markers can contribute to AD development in
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service