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S0900

Sigma-Aldrich

D-Sorbitol

suitable for electrophoresis

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
50-70-4
Molecular Weight:
182.17
Beilstein/REAXYS Number:
1721899
EC Number:
200-061-5
MDL number:
MFCD00004708
UNSPSC Code:
12352201
PubChem Substance ID:
24899452

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

≥98% (GC)

form

powder

technique(s)

electrophoresis: suitable

mp

98-100 °C (lit.)

foreign activity

Proteinase, none detected

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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Application

Sorbitol has been used in isoelectric focusing to help minimize endoosmotic flow in agarose gels,[1] and has been found to improve protein solubility of focused proteins.[2] Sorbitol has also been advocated to improve mechanical stability, improve wall adherence of the gel to the glass tube, and reduce pH gradient drift. Sorbitol is usually used at a concentration of 10-12.5%.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
071M00272V
071M00272
110M02091V
110M02091
030M01885

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Andrews, A.T.
Electrophoresis: Theory, Techniques, and Biochemical and Clinical Applications, 261-262 (1988)
Isoelectric focusing.
D E Garfin
Methods in enzymology, 182, 459-477 (1990-01-01)
Arlene E Dent et al.
PloS one, 3(10), e3557-e3557 (2008-10-30)
Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays
Anna Boccaccio et al.
Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)
Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large
Youngkook Kwon et al.
ChemSusChem, 6(3), 455-462 (2013-01-25)
This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction
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