RAB1476

Human GAPHD ELISA

for serum, plasma and cell culture supernatants

• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.82 ng/mL; standard curve range: 0.819-200 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... GAPDH(2597)

Description

General description

The GAPHD (glyceraldehyde-3-phosphate dehydrogenase) gene is mapped to human chromosome 12p13.31. GAPHD encodes a multifunctional protein which is a glycolytic enzyme.

This ELISA antibody pair detects human GAPHD. Other species not yet determined.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

GAPHD (glyceraldehyde-3-phosphate dehydrogenase) is associated with the progression of Huntington′s disease by increasing cytotoxicity. Gaphd is often referred to as glycolytic enzyme and catalyzes the sixth step in glycolysis. The Gaphd enzyme possess uracil-DNA glycosylase activity. The enzyme regulates transcription, posttranscriptional gene expression, intracellular membrane trafficking and apoptosis.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Safety Information

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable