RAB0640
Human CCL23 / C-C Motif Chemokine 23 ELISA Kit
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CCL23(6368)
General description
CCL23 (C-C motif chemokine ligand 23) codes for a member of CC chemokine family.[1] CCL23 is also known as myeloid progenitor inhibitory factor 1 and is predominantly produced by eosinophils[2] The gene is mapped to human chromosome 17q12.[3]
The antibody pair provided in this kit recognizes human CK beta 8-1 / CCL23.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
CCL23 (C-C motif chemokine ligand 23) mediates leukocyte trafficking and is associated with inflammatory diseases.[4] CCL23 is responsible for the recruitment of monocytes and macrophages through CCR1.[2] Upregulation of CCL23 is observed in chronic kidney disease and participates in the pathogenesis of atherosclerosis.[4][1]
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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Effect of diabetes and oxidative stress on plasma CCL23 levels in patients with severe chronic kidney disease.
Pawlak K, et al.
Polskie Archiwum Medycyny Wewnetrznej, 124, 459-466 (2014)
Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps.
Poposki J A, et al.
The Journal of Allergy and Clinical Immunology, 128(1), 73-81 (2011)
Potential involvement of CCL23 in atherosclerotic lesion formation/progression by the enhancement of chemotaxis, adhesion molecule expression, and MMP-2 release from monocytes.
Kim C S, et al.
Inflammation Research, 60(9), 889-895 (2011)
Xinxin Wang et al.
Clinical laboratory, 66(11) (2020-11-13)
The current study aims to investigate the clinical significance of serum macrophage migration inhib-itory factor (MIF) and C-C motif chemokine living 23 (CCL23) in patients with acute cerebral infarction (ACI). Seventy-nine patients with ACI were selected and divided into three
Yuichi Iida et al.
Journal for immunotherapy of cancer, 8(2) (2020-07-18)
Mesenchymal stem/stromal cells (MSC) accumulate and reside in tumor sites. Taking advantage of this feature in anticancer therapy, immortalized murine MSC (iMSC) were genetically altered to produce chemokine (C-C motif) ligand 19 (iMSC/CCL19), which attracts dendritic cells (DC) and T
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