R4780

RACK1 human

recombinant, expressed in E. coli, >90% (SDS-PAGE), buffered aqueous solution

• Synonym(s): Receptor for activated protein kinase C
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• recombinant: expressed in E. coli
• assay: >90% (SDS-PAGE)
• form: buffered aqueous solution
• mol wt: 37 kDa
• UniProt accession no.: P63244
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... GNB2L1(10399)

Description

Biochem/physiol Actions

RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth.

Physical form

Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)