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Key Documents

R2031

Sigma-Aldrich

Relaxin-3 human

recombinant, expressed in E. coli, >95% (SDS-PAGE), lyophilized powder

Synonym(s):

RLN3, RXN3, Relaxin 3

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About This Item

CAS Number:
UNSPSC Code:
12352202

biological source

human

recombinant

expressed in E. coli

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

(Contains two disulfide-linked subunits: A chain ~2.5 kDa B chain ~3.0 kDa)

suitability

endotoxin tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... RLN3(117579)

General description

Neuropeptide that is related to the insulin family and located in the hypothalamus

Biochem/physiol Actions

Relaxin 3 participates in neuropeptide signaling processes
Relaxin-3 also has been shown to inhibit insulin secretion from pancreatic islet cells.

Physical form

Lyophilized powder containing BSA

Reconstitution

In Phosphate buffered saline solution containing at least 0.1% serum albumin. The concentration should be ≥10 μg/mL

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Inhibitory Effect of Relaxin-3 on Insulin Secretion in Isolated Pancreas and Insulinoma.
Yamamoto, H.
Journal of AOAC (Association of Official Analytical Chemists) International, 55, 132-137 (2009)
Ying Wu et al.
Nature communications, 6, 7708-7708 (2015-07-22)
Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here we present a broadly neutralizing human monoclonal antibody with an unusual binding

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