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R0500

Sigma-Aldrich

Reichstein′s substance S

≥98% purity, powder

Synonym(s):

11-Deoxy-17-hydroxycorticosterone, 11-Deoxycortisol, 17α,21-Dihydroxy-4-pregnene-3,20-dione, 17α-Hydroxycortexone, 17,21-Dihydroxy-4-pregnene-3,20-dione, 17,21-Dihydroxyprogesterone, 4-Pregnene-17α,21-diol-3,20-dione, Cortexolone, Reichstein’s Compound S

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1 G
$55.17

$55.17

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1 G
$55.17

About This Item

Empirical Formula (Hill Notation):
C21H30O4
CAS Number:
152-58-9
Molecular Weight:
346.46
EC Number:
205-805-2
MDL number:
MFCD00003662
UNSPSC Code:
12171500
PubChem Substance ID:
24278671
NACRES:
NA.47

$55.17

List Price$61.30Save 10%
Web-Only Promotion

Available to ship onMay 01, 2025Details

Request a Bulk Order

Product Name

Reichstein′s substance S, ≥98%

Quality Level

200

assay

(Infrared Spectrum: Conforms to Structure)
≥98%

form

powder

technique(s)

titration: suitable

mp

208 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless to faint yellow or tan

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

InChI key

WHBHBVVOGNECLV-OBQKJFGGSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX7551
MKCW9239
MKCV5201
MKCV2807
MKCS5779

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E O Yablokov et al.
The Journal of steroid biochemistry and molecular biology, 208, 105793-105793 (2020-12-04)
Steroidogenesis is strictly regulated at multiple levels, as produced steroid hormones are crucial to maintain physiological functions. Cytochrome P450 enzymes are key players in adrenal steroid hormone biosynthesis and function within short redox-chains in mitochondria and endoplasmic reticulum. However, mechanisms
Roux?s Arch. Dev. Biol. (2000)
Seiichi Sakamoto et al.
Journal of natural medicines, 72(1), 32-42 (2017-11-23)
Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products.
David A Close et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(31), 13942-13947 (2010-07-21)
Corticosteroid hormones are critical for controlling metabolism, hydromineral balance, and the stress response in vertebrates. Although corticosteroid hormones have been well characterized in most vertebrate groups, the identity of the earliest vertebrate corticosteroid hormone has remained elusive. Here we provide
In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes
Gabor Bekesi
Steroids (2000)
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