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Key Documents

Q0255

Sigma-Aldrich

Quirestine

≥98% (TLC), powder

Synonym(s):

1,2,2,6,6-pentamethylquinicludinium iodide, Imechine

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About This Item

Empirical Formula (Hill Notation):
C12H24IN
CAS Number:
Molecular Weight:
309.23
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:

assay

≥98% (TLC)

form

powder

color

colorless

mp

238-242 °C (lit.)

SMILES string

[I-].CC1(C)C[C@H]2CC[N+]1(C)C(C)(C)C2

InChI

1S/C12H24N.HI/c1-11(2)8-10-6-7-13(11,5)12(3,4)9-10;/h10H,6-9H2,1-5H3;1H/q+1;/p-1/t10-,13?;

InChI key

XFWGKJZCFAREHL-CUWJETGQSA-M

Biochem/physiol Actions

Nicotinic acetylcholine receptor antagonist. Potent short-acting ganglioblocker.

Caution

Protect from light.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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G A Buznikov et al.
General pharmacology, 29(1), 49-53 (1997-07-01)
1. Some nicotinic antagonists (piperidine and quinuclidine derivatives and bis-quaternary compounds) protect early embryos of the sea urchin Lytechinus pictus against a calcium shock evoked by ionomycin or a mixture of phorbol myristate acetate and nicotine. 2. Maximal protective potency

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