NIPSNAP2 (nipsnap homolog 2) belongs to the NIPSNAP family. It is also known as GBAS (glioblastoma amplified sequence). It is located in the mitochondrial inner membrane space. It is highly expressed in skeletal muscle and heart. GBAS codes for a protein, that has tyrosine phosphorylation sites and a transmembrane domain. It is co-amplified with EGFR (epidermal growth factor receptor gene). It is located on chromosome 7p11.2.
Immunogen
a 14 amino acid peptide near the center of human NIPSNAP2.
Biochem/physiol Actions
NIPSNAP2 (nipsnap homolog 2) plays a major role in transcriptional regulation via L-type Ca2+ channels.
Linkage
The action of this antibody can be blocked using blocking peptide SBP4953.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR
Wang XY, et al.
Genomics, 49(3), 448-451 (1998)
De novo 393 kb microdeletion of 7p11.2 characterized by aCGH in a boy with psychomotor retardation and dysmorphic features
Varvagiannis K, et al.
Meta Gene, 2, 274-282 (2014)
NIP-SNAP-1 and -2 mitochondrial proteins are maintained by heat shock protein 60
Yamamoto S, et al.
Biochemical and Biophysical Research Communications, 483(3), 917-922 (2017)
Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission
Okuda-Ashitaka E, et al.
The Journal of Biological Chemistry, 287(13), 10403-10413 (2012)
Regulation of CREB signaling through L-type Ca2+ channels by Nipsnap-2
Brittain JM, et al.
Channels (Austin, Tex.), 6(2), 94-102 (2012)
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
