a peptide corresponding to amino acids 279-296 of human MyD88, which is identical to mouse.
Linkage
The action of this antibody can be blocked using blocking peptide SBP2127.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
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The Journal of biological chemistry, 287(37), 30993-31002 (2012-07-26)
TIR (Toll/IL-1 receptor) domains mediate interactions between TLR (Toll-like) or IL-1 family receptors and signaling adapters. While homotypic TIR domain interactions mediate receptor activation they are also usurped by microbial TIR domain containing proteins for immunosuppression. Here we show the
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