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Key Documents

PLA0297

Sigma-Aldrich

Goat anti-HdmX/MDM4 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

Double minute 4 protein, HDMX, MDM4 protein variant G, MDM4 protein variant Y, MDM4-related protein 1, MDMX, MRP1, Mdm4, Mdm4 p53 binding protein homolog, Mdm4 p53 binding protein homolog (mouse), double minute 4, human homolog of; p53-binding protein, mdm2-like p53-binding protein, mouse double minute 4, p53 binding protein (mouse), p53-binding protein Mdm4, protein Mdmx, transformed 3T3 cell double minute 4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

concentration

1 mg/mL

technique(s)

immunoprecipitation (IP): 2-10 μg/mg

accession no.

NP_002384.2

shipped in

wet ice

storage temp.

2-8°C

Gene Information

Immunogen

The epitope recognized by PLA0297 maps to a region between residue 150 and 200 of human Ortholog of Mouse Double Minute 4 using the numbering given in entry NP_002384.1 (GeneID 4194).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

HdmX/MDM4 is a RING-finger domain containing protein that interacts with p53. HdmX/MDM4 may influence p53 stability through an interaction with the structurally similar MDM2, an ubiquitin-ligase that targets p53 for proteasomal degradation. HdmX/MDM4 may influence p53 by directly attenuating p53 transcriptional activity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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