PLA0170

Rabbit anti-NCoR Antibody, Affinity Purified

• Synonym(s): KIAA1047, MGC104216, N-CoR, N-CoR1, PPP1R109, TRAC1, hCIT529I10, hN-CoR, nuclear receptor co-repressor 1, protein phosphatase 1, regulatory subunit 109, thyroid hormone- and retinoic acid receptor-associated corepressor 1
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: mouse, human
• technique(s): immunoprecipitation (IP): 2-10 μg/mg; proximity ligation assay: 10 μg; western blot: 1:2,000- 1:10,000
• accession no.: NP_006302.2
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... NCoR(9611)

Description

Immunogen

The epitope recognized by PLA0170 maps to a region between residue 1525 and 1575 of human nuclear receptor co-repressor 1 using the numbering given in entry NP_006302.2 (GeneID 9611).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

The nuclear Receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable