PLA0147

Rabbit anti-TIF1 Alpha/TRIM24 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): E3 ubiquitin-protein ligase TRIM24, PTC6, RING finger protein 82, RNF82, TF1A, TIF1, TIF1-alpha, TIF1A, TIF1ALPHA, Tripartite motif-containing protein 24, hTIF1, transcriptional intermediary factor 1, tripartite motif-containing 24
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human, mouse
• technique(s): ChIP: 4-30 μg; immunohistochemistry: 1:200- 1:1,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000- 1:10,000
• accession no.: NP_056989.2
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... TRIM24(8805)

Description

Immunogen

The epitope recognized by PLA0147 maps to a region between residue 700 and 750 of human Transcriptional Intermediary Factor 1 Alpha (Tripartite Motif-Containing 24 ) using the numbering given in entry NP_056989.2 (GeneID 8805).

Physical form

Tris-buffered Saline containing 0.1% BSA with 0.09% Sodium Azide

Other Notes

TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable