PLA0087

Rabbit anti-MAD2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): HSMAD2, MAD2, MAD2 (mitotic arrest deficient, MAD2-like protein 1, homolog)-like 1, homolog-like 1, mitotic arrest deficient, mitotic arrest deficient 2-like protein 1, yeast
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human, mouse
• technique(s): immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000-1:10,000
• accession no.: Q13257
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: rabbit ... MAD2(4085)

Description

Immunogen

The epitope recognized by PLA0087 maps to a region between residue 150 and the C-terminus (residue 205) of human Mitotic Arrest Deficient 2 using the numbering given in SwissProt entry Q13257 (GeneID 4085).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

MAD2 (Mitotic Arrest Deficiency 2) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD2 is a subunit of the MCC complex that includes BubR1, Bub3, Cdc20 and Mad2, which may function to inhibit the APC/c (Anaphase Promoting Complex/Cyclosome). MAD2 is regulated by MAD1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable