PLA0058

Rabbit anti-Rad50 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): NBSLD, RAD50 (S. cerevisiae) homolog, RAD50 homolog, RAD50 homolog (S. cerevisiae), RAD50-2, RAD502, double strand break repair protein, hRad50
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: human
• technique(s): immunoprecipitation (IP): 1- 4 μg/mg; western blot: 1:1,000-1:5,000
• accession no.: NP_005723.2
• UniProt accession no.: Q92878
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... Rad50(10111)

Description

Immunogen

The epitope recognized by PLA0058 maps to a region between residues 50 and 100 of human Rad50 using the numbering given in entry NP_005723.2 (GeneID 10111).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable