The epitope recognized by PLA0021 maps to a region between residues 250 and 300 of human Cell Division Cycle 25A using the numbering given in entry NP_001780.2 (GeneID 993).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
Other Notes
CDC25a is a member of the CDC25 family of protein phosphatases. CDC25 is involved in promoting the G1 to S phase as well as the G2 to M phase transition of the cell cycle by removing inhibitory phosphates from tyrosine and threonine residues of cyclin-dependent kinases (CDKs). CDC25a is an oncogene and has been found to be overexpressed in a subset of human cancers.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
