P9868
Anti-Protein Phosphatase 5 (PP5) antibody produced in rabbit
buffered aqueous solution, fractionated antiserum, pkg of ~100 μg, 1 mg/mL
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About This Item
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 58 kDa
species reactivity
human
packaging
pkg of ~100 μg
concentration
1 mg/mL
technique(s)
western blot: 5-10 μg/mL using A549 or MCF7 cell lysates
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PPP5C(5536)
General description
Ser/Thr protein phosphatase type 5 (PP5) is a 58kD protein present in human and is localized in nucleus which plays an essential role in mitosis and in the regulation of RNA biogenesis. It also has a pivotal role in cell proliferation and facilitates neoplastic transformation. Rabbit Anti-Protein Phosphatase 5 (PP5) antibody can identify human PP5 and reacts specifically with protein serine threonine phosphatase 5 (58 kD).
Immunogen
synthetic peptide derived from the human phosphatase 5 protein.
Application
Anti-Protein Phosphatase 5 (PP5) antibody can be used in western blotting using A549 or MCF7 cell lysates.
Physical form
Solution in phosphate buffered saline containing 0.08% sodium azide. The amount of the reagent is sufficient for 10 blots.
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Storage Class
10 - Combustible liquids
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M Chinkers
Trends in endocrinology and metabolism: TEM, 12(1), 28-32 (2001-01-04)
Protein phosphatase 5 (PP5) possesses unique biochemical properties, which include its tetratricopeptide repeat (TPR) targeting/regulatory domain and its ability to be activated by lipids. PP5 has been studied as a paradigm for TPR protein structure and function. Roles for PP5
Z Zuo et al.
Biochemistry, 38(28), 8849-8857 (1999-07-22)
Ligand-induced glucocorticoid receptor (GR) activation has recently been linked to the inhibition of cell proliferation via the transcriptional induction of p21(WAF1/Cip1), which functions as a universal inhibitor of cyclin-dependent protein kinases. Herein, we identify a Ser/Thr protein phosphatase (PP5) that
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