P8872
Anti-Pituitary Adenylate Cyclase Activating Polypeptide Type 1 Receptor antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-PACAP Receptor Type 1
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About This Item
MDL number:
UNSPSC Code:
12352203
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
availability
not available in Japan
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 7 μg/mL using human pituitary
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ADCYAP1R1(117)
Immunogen
synthetic peptide corresponding to the N-terminal extracellular domain of human pituitary adenylate cyclase activating polypeptide type 1 receptor (PACAP), conjugated to KLH. The immunizing peptide has 94% homology with the rat and mouse gene.
Target description
Pituitary Adenylate Cyclase-Activating Polypeptide is present not only in the central nervous system but also in peripheral tissues,including the gastrointestinal tract, adrenal gland, andtestes. Its actions include the stimulation of secretion ofgr
Physical form
Solution in phosphate buffered saline containing 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Ildiko Somogyi et al.
Annals of the New York Academy of Sciences, 1163, 521-523 (2009-05-22)
By means of radioimmunoassay, we studied the concentration of pituitary adenylate cyclase-activating polypeptide (PACAP)-like proteins in intact and regenerating earthworms. Transection of animals increased the concentration of PACAP-like compounds in coelomocytes, and a decreasing rostrocaudal gradient was detected in the
P Egri et al.
Endocrinology, 157(6), 2356-2366 (2016-04-06)
The hypothalamic activation of thyroid hormones by type 2 deiodinase (D2), catalyzing the conversion of thyroxine to T3, is critical for the proper function of the hypothalamo-pituitary-thyroid (HPT) axis. Regulation of D2 expression in tanycytes alters the activity of the
Jacqueline Hill et al.
American journal of physiology. Cell physiology, 303(3), C257-C266 (2012-05-18)
Neuroendocrine adrenal medullary chromaffin cells receive synaptic excitation through the sympathetic splanchnic nerve to elicit catecholamine release into the circulation. Under basal sympathetic tone, splanchnic-released acetylcholine evokes chromaffin cells to fire action potentials, leading to synchronous phasic catecholamine release. Under
Tamás Juhász et al.
International journal of molecular sciences, 16(8), 17344-17367 (2015-08-01)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neurohormone exerting protective function during various stress conditions either in mature or developing tissues. Previously we proved the presence of PACAP signaling elements in chicken limb bud-derived chondrogenic cells in micromass cell
Nóra Krajcs et al.
Journal of molecular neuroscience : MN, 57(4), 492-500 (2015-07-04)
In this study, we investigate the potentiating effect of PACAP27 on cholinergic neuromuscular transmission in the recently discovered flexor muscles of the land snail, Helix pomatia. Using immunohistochemistry, we show that PACAP and PAC1 receptors are present in nerve fibers
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