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Key Documents

P8757

Sigma-Aldrich

4-Pregnene-17α,20β,21-triol-3,11-dione

Synonym(s):

17α,20β,21-Trihydroxy-4-pregnene-3,11-dione, 20β-Dihydrocortisone, Reichstein’s substance U

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About This Item

Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
116-59-6
Molecular Weight:
362.46
UNSPSC Code:
12352200
PubChem Substance ID:
329820336

form

solid

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,17-18,22,25-26H,3-8,10-11H2,1-2H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1

InChI key

XBIDABJJGYNJTK-GNIMZFFESA-N

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
094F4016
036H4033
094F4017

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H Tveiten et al.
Journal of fish biology, 77(1), 33-53 (2010-07-22)
Atlantic cod Gadus morhua ovaries were incubated in vitro with tritiated 17-hydroxypregn-4-ene-3,20-dione (17-P) to determine whether 17,20beta-dihydroxypregn-4-en-3-one (17,20beta-P) or 17,20beta, 21-trihydroxypregn-4-en-3-one (17,20beta,21-P), or both, were more likely to be the steroid responsible for inducing oocyte final maturation (i.e. resumption of
H M Dodds et al.
Analytical biochemistry, 247(2), 342-347 (1997-05-01)
A reversed-phase high-performance liquid chromatography-electrospray-tandem mass spectrometry assay (HPLC-ESI-MS/MS) was developed to quantitate cortisol, cortisone, 20 alpha- and beta-dihydrocortisol, 20 alpha- and beta-dihydrocortisone, tetrahydrocortisol, and tetrahydrocortisone. The technique was used to analyze perfusate from the isolated human placental lobule for
M A Popot et al.
Equine veterinary journal, 31(4), 278-284 (1999-08-24)
The cortisol threshold concentration of 1.0 microg/ml in horse urine adopted by the International Federation of the racing Authorities in 1994 is specific. However, an increase in the sensitivity for the detection of cortisol administration would be helpful. Previous studies

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