Polyacrylate-polyalcohol is a high molecular weight polymer, which is insoluble in water. It expands as it absorbs water and may pick up to 300 times its weight in water. Because of its high molecular weight, the polymer is safe to use with dialysis tubing of any molecular weight cut-off without fear of its passing through the pores of the dialysis membrane and contaminating the sample solution. The swollen polymer rinses off easily, unlike some adsorbents, which may partially dissolve and form viscous films on membrane surfaces. Polyacrylate-polyalcohol is designed to concentrate any molecule that has a molecular weight larger than the molecular weight cut-off (MWCO) of the dialysis tubing or membrane being used. It can be used with as little as 100 μL of solution.
Application
Polyacrylate-polyalcohol is used in protein chromatography and affinity chromatography. Polyacrylate-polyalcohol has been used to study the treatment of vesicoureteric reflux (VUR). Very useful for concentrating solutions of proteins, DNA or microparticles.
The Journal of urology, 183(2), 714-717 (2009-12-22)
We report the preliminary results of endoscopic treatment of vesicoureteral reflux in children using polyacrylate polyalcohol copolymer. We performed a prospective multicenter review of pediatric patients treated with subureteral injection of a new nonabsorbable substance. Only patients with 1 year
Archivos espanoles de urologia, 61(2), 263-268 (2008-05-22)
Biodegradable injectable bulking agents of animal origin present a fast rate of bio-reabsorption and may cause an allergic reaction. Biodegradable elements of synthetic origin have a high rate of reabsorption after a year. Non-biodegradable agents of synthetic origin lead to
Journal of pediatric urology, 7(6), 654-657 (2011-01-05)
The aim of this study was to evaluate the efficacy of single injection of a new non-biodegradable agent (Vantris(®)) Manufactured by Promedon, Cordoba, Argentina for treatment of vesicoureteric reflux (VUR). 38 children (11 males and 27 females) with a mean
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