All Photos(1)

Key Documents

COO/COA

P6835

Poly(Glu, Tyr)−Agarose

Name: Poly(Glu, Tyr)−Agarose
Brand: SIGMA

Glu:Tyr (4:1), saline suspension

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

MDL number:

MFCD00677697

UNSPSC Code:

12352200

NACRES:

NA.26

This product is discontinued. Contact Technical Servicefor assistance.

form

saline suspension

feed ratio

Glu:Tyr (4:1)

extent of labeling

12-15 mg per mL gel

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

carboxyl

matrix spacer

8 atoms

storage temp.

2-8°C

Application

Useful for the purification of tyrosine kinase

Physical form

Suspension in 1.0 M NaCl containing preservative

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Partial purification and characterization of protein tyrosine kinases from normal tissues.

S Braun et al.

Archives of biochemistry and biophysics, 247(2), 424-432 (1986-06-01)

Three membranous protein tyrosine kinases (PTKs) have been partially purified from human placenta and pig brain. The two placental enzymes (PTK-1 and -2) are distinct with respect to solubility in detergents, molecular weight, and enzymatic properties. The brain protein tyrosine

Inhibition of motility of hamster spermatozoa by protein tyrosine kinase inhibitors.

K Uma Devi et al.

Andrologia, 32(2), 95-106 (2001-02-07)

Genistein, tyrphostin and piceatannol, which are specific inhibitors of protein tyrosine kinase, were screened for their effects on the motility of intact and demembranated hamster spermatozoa. Of the three inhibitors only piceatannol inhibited the motility of intact spermatozoa. None of

Identification of the proteins present in the bull sperm cytosolic fraction enriched in tyrosine kinase activity: a proteomic approach.

Claudia Lalancette et al.

Proteomics, 6(16), 4523-4540 (2006-07-19)

Numerous sperm proteins have been identified on the basis of their increase in tyrosine phosphorylation during capacitation. However, the tyrosine kinases present in spermatozoa that are responsible for this phosphorylation remain unknown. As spermatozoa are devoid of transcriptional and translational

DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.

S R Mullapudi et al.

The Biochemical journal, 351 Pt 2, 393-402 (2000-10-12)

We showed recently that human O(6)-alkylguanine-DNA alkyltransferase (AGT), an important target for improving cancer chemotherapy, is a phosphoprotein and that phosphorylation inhibits its activity [Srivenugopal, Mullapudi, Shou, Hazra and Ali-Osman (2000) Cancer Res. 60, 282-287]. In the present study we

Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service