synthetic peptide corresponding to the N-terminal extracellular domain of human parathyroid hormone receptor 1 conjugated to KLH. The immunizing peptide has 80% homology with the rat and mouse gene.
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Parathyroid Hormone Receptor 1 is a G protein-coupled receptor that binds parathyroid hormone (PTH) and PTH related peptide. The key functions of PTHR1 is the regulation of biochemical processes in kidney, bone and other tissues, as well as maintaining the concentrations of calcium and phosphate ions, and vitamin D in blood and extracellular fluids.
The striking clinical benefit of PTH in osteoporosis began a new era of skeletal anabolic agents. Several studies have been performed, new studies are emerging out and yet controversies remain on PTH anabolic action in bone. This review focuses on
In a group of 45 patients treated by chronic dialysis the author followed up during 38 months the nutritional status influenced by various complications. For detection of nutritional disorders the author selected albumin, prealbumin, transferrin, Whitehead's quotient (WQ). The most
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