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Key Documents

P6122

Sigma-Aldrich

Anti-Parathyroid Hormone Receptor 1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-PTHR1

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human kidney, collecting ducts of the cortex.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... PTH1R(5745)
mouse ... Pth1r(19228)
rat ... Pthr1(56813)

Immunogen

synthetic peptide corresponding to the N-terminal extracellular domain of human parathyroid hormone receptor 1 conjugated to KLH. The immunizing peptide has 80% homology with the rat and mouse gene.

Biochem/physiol Actions

Parathyroid Hormone Receptor 1 is a G protein-coupled receptor that binds parathyroid hormone (PTH) and PTH related peptide. The key functions of PTHR1 is the regulation of biochemical processes in kidney, bone and other tissues, as well as maintaining the concentrations of calcium and phosphate ions, and vitamin D in blood and extracellular fluids.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Nabanita S Datta et al.
Cellular signalling, 21(8), 1245-1254 (2009-03-03)
The striking clinical benefit of PTH in osteoporosis began a new era of skeletal anabolic agents. Several studies have been performed, new studies are emerging out and yet controversies remain on PTH anabolic action in bone. This review focuses on
H Fischerová
Casopis lekaru ceskych, 130(14), 431-435 (1991-05-24)
In a group of 45 patients treated by chronic dialysis the author followed up during 38 months the nutritional status influenced by various complications. For detection of nutritional disorders the author selected albumin, prealbumin, transferrin, Whitehead's quotient (WQ). The most

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