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Key Documents

P5435

Sigma-Aldrich

Monoclonal Anti-CD14−PE antibody produced in mouse

clone UCHM-1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Monoclonal Anti-CD14

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About This Item

UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

UCHM-1, monoclonal

form

buffered aqueous solution

mol wt

antigen 55 kDa

species reactivity

human

technique(s)

flow cytometry: 10 μL using 1 × 106 cells

isotype

IgG2a

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... CD14(929)

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Specificity

The epitope recognized by this clone is sensitive to routine formalin fixation and paraffin embedding. Cryostat sections, post-fixed in formalin can be stained.
3rd Workshop: code no. 203
4th Workshop: code no. M24

Immunogen

human thymocytes followed by peripheral blood T cells.

Target description

CD14 is a phosphoinositol-linked, single-chain, human cell surface glycoprotein antigen which is found on most human peripheral blood monocytes, granulocytes and dendritic reticulum cells, and some tissue macrophages. CD14 may also be present on B cells. Soluble forms of CD14 are present in serum and urine. The antigen functions as an acceptor for LPS-binding protein complexes.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Preparation Note

Prepared by conjugation to R-phycoerythrin (PE). This orange-red dye is efficiently excited at 488 nm and emits at 578 nm.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Justyna Trynda et al.
International journal of molecular sciences, 16(10), 24873-24894 (2015-10-23)
Analogs of 1,25-dihydroxyergocalciferol, modified in the side-chain and in the A-ring, were tested for their antiproliferative activity against a series of human cancer cell lines in vitro and in vivo toxicity. The proliferation inhibition caused by the analogs was higher

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