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P4898

Sigma-Aldrich

Phe-Met-Arg-Phe amide

≥95% (HPLC)

Synonym(s):

FMRF amide, Molluscan cardioexcitatory neuropeptide

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About This Item

Empirical Formula (Hill Notation):
C29H42N8O4S
CAS Number:
64190-70-1
Molecular Weight:
598.76
MDL number:
MFCD00076625
UNSPSC Code:
12352200
PubChem Substance ID:
24898566

assay

≥95% (HPLC)

form

powder

composition

Peptide content, ~65%

technique(s)

mass spectrometry (MS): suitable

color

white

storage temp.

−20°C

SMILES string

CSCCC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc2ccccc2)C(N)=O

InChI

1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)

InChI key

WCSPDMCSKYUFBX-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLBB2107V
031M1904V
120M1236V
120M1236
010M1364

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Tamás Röszer et al.
Brain, behavior and evolution, 63(1), 23-33 (2003-12-16)
The anatomical and functional relationship between neurons expressing nitric oxide (NO) synthase and molluscan cardioexcitatory (FMRFamide)-like neuropeptides was studied in the central ganglia of Helix lucorum (Pulmonata, Gastropoda), applying NADPHdiaphorase (NADPHd) histochemistry to visualize NO synthase and immunocytochemistry to demonstrate
Tamás Roszer et al.
Cell and tissue research, 325(3), 567-575 (2006-04-14)
The possible involvement of the L-arginine-containing Phe-met-arg-phe (FMRF)-amide (FMRFa) in neuronal nitric oxide (NO) biosynthesis was studied in a gastropod species. We found NADPH-diaphorase-positive neurons and FMRFa-containing fibers in close proximity in the enteric nervous system. Administration of L-arginine and
Abdesslam Chrachri et al.
The European journal of neuroscience, 17(3), 526-536 (2003-02-13)
The effects of the neuropeptide FMRFa on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs), as well as on evoked EPSCs and IPSCs, in two types of neurons within the central optic lobe of cuttlefish were examined using
Luke A Hoekstra et al.
PloS one, 7(9), e44220-e44220 (2012-09-13)
Understanding of the echinoderm nervous system is limited due to its distinct organization in comparison to other animal phyla and by the difficulty in accessing it. The transparent and accessible, apodid sea cucumber Leptosynapta clarki provides novel opportunities for detailed
Tatiana Mayorova et al.
Zoology (Jena, Germany), 116(1), 9-19 (2012-12-12)
Gonothyraea loveni (Allman, 1859) is a colonial thecate hydrozoan with a life cycle that lacks a free-swimming medusa stage. The development from zygote to planula occurs within meconidia attached to the female colony. The planula metamorphosis results in the formation
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