Journal of medicinal chemistry, 56(12), 4953-4965 (2013-06-06)
We recently reported the discovery of H-Phe-Phe-NH2 as a small and high affinity ligand for the substance P 1-7 (SP(1-7), H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH) specific binding site and its intriguing ability to reduce neuropathic pain. With the overall aim to develop stable and
Journal of molecular graphics & modelling, 29(2), 178-187 (2010-07-09)
An evaluation of a dispersion-corrected density functional theory method (B3LYP-DCP) [I.D. Mackie, G.A. DiLabio, Interactions in large, polyaromatic hydrocarbon dimers: application of density functional theory with dispersion corrections, J. Phys. Chem. A 112 (2008) 10968-10976] for three systems of biochemical
Journal of magnetic resonance (San Diego, Calif. : 1997), 313, 106717-106717 (2020-04-03)
The advent of ultrahigh magnetic field and fast magic-angle-spinning (MAS) probe technology has led to dramatically enhanced spectral resolution and sensitivity in solid-state NMR spectroscopy. In particular, proton-based multidimensional solid-state NMR techniques have become feasible to investigate the structure and
Peptidic self-assembled nanostructures are said to have a wide range of applications in nanotechnology, yet the mechanistic details of hierarchical self-assembly are still poorly understood. The Phe-Phe recognition motif of the Alzheimer's Abeta peptide is the smallest peptide able to
Potential advantages of C2-symmetric inhibitors designed for the symmetric HIV-1 protease include high selectivity, potency, stability, and bioavailability. Pseudo-C2-symmetric monools and C2-symmetric diols, containing central hydroxymethylene and (R,R)-dihydroxyethylene moieties flanked by a variety of hydrophobic P1/P1' side chains, were studied
Is the powder crystalline? are there water molecules trapped inside it?
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Technical Support
·11 months ago
The product is considered a 'powder' rather than 'crystalline'. There is typically water present in this material. This information is lot specific and reported in the Certificate of Analysis. While there is not specification in place, recent lots have reported a range of 7.2 - 9.2%. Please see the link below to review a sample or lot specific Certificate: https://www.sigmaaldrich.com/product/sigma/p4126#product-documentation
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