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P2740

Sigma-Aldrich

Presenilin-2 N-Terminal Peptide

lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352202

description

Equivalent to technical grade. Purity may be less than 50%.

assay

≥85% (HPLC)

form

lyophilized powder

species reactivity

human

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... PSEN2(5664)

Amino Acid Sequence

Cys-Gln-Glu-Gly-Arg-Gln-Gly-Pro-Glu-Asp-Gly-Glu-Asn-Thr-Ala-Gln

Biochem/physiol Actions

Peptide used to study effects on the production of Aβ[X-42] peptide and accumulation of endogenous presenilin.
Product used to study production of Aβ[X-42] peptide and accumulation of endogenous presenilin.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Kenneth R McLeish et al.
Journal of leukocyte biology, 102(1), 19-29 (2017-01-18)
Neutrophil granule exocytosis plays an important role in innate and adaptive immune responses. The present study examined TNF-α stimulation or priming of exocytosis of the 4 neutrophil granule subsets. TNF-α stimulated exocytosis of secretory vesicles and gelatinase granules and primed

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