P1491
Anti-phospho-p38 (pThr180/pTyr182) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
Synonym(s):
SAPKJ/MAPK, Stress Activated Protein Kinase/MAP Kinase
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About This Item
MDL number:
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antibody apparent mol wt ~43 kDa
species reactivity
mouse, canine, rat, carp, human, monkey
technique(s)
immunohistochemistry: suitable
western blot: 1:1000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... MAPK14(1432)
mouse ... Mapk14(26416)
rat ... Mapk14(81649)
General description
P38 is a mitogen-activated protein kinase (MAPK) that belongs to serine/threonine protein kinase family and is a member of the stress-activated protein kinases (SAPK). P38 signaling pathway regulates inflammatory responses, apoptosis, cell proliferation and differentiation. Dually phosphorylated p38 (i.e (Thr180) and (Tyr182)) is a 43kD endogenous protein that belongs to High Osmolarity Glycerol response kinase (HOG). Anti-phospho-p38 (pThr180/pTyr182) antibody can be used in immunostaining and immunohistochemistry. Rabbit anti-phospho-p38 (pThr180/pTyr182) antibody reacts specifically with p38 of rat and human. This product is also reactive for endogenous, active forms of p38 α, β, γ (43kD).
Immunogen
synthetic phosphopeptide derived from the region of p38 that contains threonine180 and tyrosine182 based on the human sequence.
Application
Anti-phospho-p38 (pThr180/pTyr182) antibody can be used in immunofluorescence. It can also be used in western blotting (diluted 1: 1000).
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3 with 50% glycerol, 1 mg/ml BSA and 0.05% sodium azide as a preservative.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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