Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).
Prostaglandins, leukotrienes, and essential fatty acids, 65(5-6), 271-280 (2002-05-08)
This paper describes a new iodine-125 radioimmunoassay of 9alpha ,11beta-PGF2, and its use for the determination of urinary 9alpha,11beta-prostaglandin F2 after a selective one-step solid-phase extraction. The newly reported immunoassay is based on the use of 125I-tyrosyl methyl ester derivative
It has recently been shown that prostaglandin (PG)E2 or F2 alpha reduces the intraocular pressure (IOP) of cats and primates when applied topically to the eye in very small doses, and that reduced IOP can be maintained in these species
Japanese journal of ophthalmology, 32(4), 471-480 (1988-01-01)
Studies were carried out of the effects of topically applied prostaglandin (PG) D2 and its metabolites and analogues on the intraocular pressure (IOP) in rabbits, and the results were compared with those of studies using PGE2 and F2 alpha. The
[Separation and determination of dl-15-methyl PGF2 alpha and its methyl ester by HPLC].
X L Lu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 22(12), 901-907 (1987-12-01)
Acta obstetricia et gynecologica Scandinavica, 65(2), 175-180 (1986-01-01)
The hysterometric technique has been designed to measure the pharmacological effect of active agents upon the human uterine muscle. The physiological background is the fact that smooth muscle contracts under the influence of mechanical stimulation. By applying hysterometry, the effects
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