synthetic peptide corresponding to the N-terminal extracellular domain of human oxytocin receptor. The immunizing peptide has 95% homology with the rat and mouse gene.
Application
Anti-Oxytocin Receptor antibody produced in rabbit was used in immunoblotting analysis of proteins extracted from bovine T lymphocytes.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper)
Biochem/physiol Actions
Oxytocin is a nonapeptide hormone that influences the social behavior in mammals that live in groups. Oxytocin binds to oxytocin receptor (OXTR) and regulates the ability to socially communicate and comprehend vocal communication. Polymorphisms in gene that codes of this receptor are associated with the severity of communication defects commonly observed in autism.
Physical form
Solution in phosphate buffered saline containing 0.1% sodium azide.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Frontiers in human neuroscience, 7, 801-801 (2013-12-19)
Although cooperation represents a core facet of human social behavior there exists considerable variability across people in terms of the tendency to cooperate. One factor that may contribute to individual differences in cooperation is a key gene within the oxytocin
Biology of reproduction, 78(4), 786-793 (2007-12-21)
The corpus luteum (CL) produces oxytocin (OXT), which has been proposed to regulate the pulsatile release of prostaglandin F2alpha during luteolysis in ruminants. This action of OXT is mediated via oxytocin receptors (OXTRs) present on uterine epithelial cells. It is
Persistent breeding-induced endometritis (PBIE) or delayed uterine clearance (DUC) are major causes of mare subfertility. Oxytocin and its receptor are thought to play significant roles in the pathogenesis of DUC but the specific roles of oxytocin receptor (OR) distribution and
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