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About This Item
Empirical Formula (Hill Notation):
C15H24N2O2
CAS Number:
Molecular Weight:
264.36
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
assay
≥98% (HPLC)
Quality Level
form
powder
solubility
methanol: 10 mg/mL, clear, colorless
Storage temp.
2-8°C
SMILES string
[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23
InChI
1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
Inchi Key
XVPBINOPNYFXID-LHDUFFHYSA-N
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Biochem/physiol Actions
Alkaloid isolated from Sophora flavescens. Antifribotic. Neuroprotective. Traditional chinese medicine used in the treatment against hepatitis B virus.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Xiaopei Yuan et al.
Journal of ethnopharmacology, 137(3), 1477-1485 (2011-09-01)
The combination of Radix Angelicae sinensis (Oliv.) Diels and Radix Sophora flavescens Ait. was extensively used in traditional Chinese medicine to treat inflammatory diseases, such as acne, heart disease, and hepatitis. Sodium ferulate (SF) and oxymatrine (OMT) were effective component
Yan-Yan Zhang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(2), 626-635 (2017-09-26)
Doxorubicin-induced cardiac toxicity has been a major concern of oncologists and is considered the main restriction on its clinical application. Oxymatrine has shown potent anti-cancer, anti-fibrosis, and anti-oxidative effects. Recently, it has been reported that oxymatrine is protective against some
Man Huang et al.
Journal of ethnopharmacology, 143(1), 228-235 (2012-07-04)
Oxymatrine is extracted from the traditional Chinese herb Sophora flavescens Ait, possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, and has been used for the treatment of chronic viral hepatitis and many other diseases. This study aimed to investigate the effects of
Ruiying Wang et al.
Stem cell research & therapy, 10(1), 20-20 (2019-01-13)
Cardiotoxicity remains an important concern in drug discovery and clinical medication. Meanwhile, Sophora tonkinensis Gapnep. (S. tonkinensis) held great value in the clinical application of traditional Chinese medicine, but cardiotoxic effects were reported, with matrine, oxymatrine, cytisine, and sophocarpine being
Noriko Funaya et al.
Journal of chromatography. A, 1248, 18-23 (2012-06-15)
Matrine (MT)- and oxymatrine (OMT)-imprinted monodisperse polymers have been prepared by precipitation polymerization. The prepared molecularly imprinted polymers (MIPs) for MT and OMT, MIP(MT) and MIP(OMT), were monodispersed microspheres of 3.3 and 3.9 μm in diameter, respectively. Binding experiments and
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