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Key Documents

N9285

Sigma-Aldrich

Nuclear Transport Factor 2−Agarose

saline suspension

Synonym(s):

NTF2−Agarose

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.56

form

saline suspension

extent of labeling

1.5-3.0 mg per mL

matrix

fast flow highly cross-linked 4% beaded agarose

matrix spacer

6 atoms

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

NTF2 is a small homodimeric protein that interacts simultaneously with both Ran-GDP and FxFG nucleoporins. The interaction between NTF2 and Ran-GDP is essential for the import of Ran into the nucleus, thus crucial for maintaining the cellular nuclear transport and cell viability. NTF2-agarose affinity resin is a useful tool for studying nuclear transport and the depletion of Ran-GDP from cell extracts.

Physical form

Suspension in 1 M sodium chloride containing 0.02% thimerosal.

Analysis Note

Measured in a binding assay of Ran-GDP to NTF2-agarose.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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