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N6523

Sigma-Aldrich

Anti-Nephronophthisis (NPH) (pic) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
PubChem Substance ID:
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 90 kDa

species reactivity

mouse

technique(s)

immunoprecipitation (IP): 10-20 μg/mL
western blot: 2-10 μg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2)C(O)=O)c34

Gene Information

mouse ... Nphp1(53885)

Related Categories

General description

Nephronophthisis 1 homolog (Nph) is highly expressed in mouse testis.

Immunogen

GST fusion protein corresponding to amino acids 612-691 of mouse NPH.

Biochem/physiol Actions

Studies have shown that male mice with a mutant nephronophthisis 1 homolog (Nph) protein turn out to be infertile.

Physical form

Solution in phosphate buffered saline containing 0.08% sodium azide.

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Storage Class

10 - Combustible liquids


Certificates of Analysis (COA)

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Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice.
Jiang ST
Human Molecular Genetics, 17(21), 3368-3379 (2008)

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