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N5537

Sigma-Aldrich

NDNI hydriodide

solid, (The product is pure based on CHN, NMR, MS)

Synonym(s):

N-n-Decylnicotinium iodide hydriodide

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About This Item

Empirical Formula (Hill Notation):
C20H36I2N2
CAS Number:
Molecular Weight:
558.32
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

form

solid

storage condition

protect from light

color

light yellow

solubility

H2O: ~15 mg/mL

SMILES string

[I-].I[H].CCCCCCCCCC[n+]1cccc(c1)[C@@H]2CCCN2C

InChI

1S/C20H35N2.2HI/c1-3-4-5-6-7-8-9-10-16-22-17-11-13-19(18-22)20-14-12-15-21(20)2;;/h11,13,17-18,20H,3-10,12,14-16H2,1-2H3;2*1H/q+1;;/p-1/t20-;;/m0../s1

InChI key

NNVBWSUAQNYTGZ-FJSYBICCSA-M

Biochem/physiol Actions

Highly selective α4β2 nicotinic receptor antagonist

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Lincoln H Wilkins et al.
The Journal of pharmacology and experimental therapeutics, 304(1), 400-410 (2002-12-20)
The current study demonstrates that N-n-alkylnicotinium analogs with increasing n-alkyl chain lengths from 1 to 12 carbons have varying affinity (Ki = 90 nM-20 microM) for S-(-)-[3H]nicotine binding sites in rat striatal membranes. A linear relationship was observed such that

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