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Key Documents

N4415

Sigma-Aldrich

NGA2F Glycan

from Porcine

Synonym(s):

(GlcNAc)2Man3(Fuc)(GlcNAc)2, Asialo, agalacto, biantennary N-glycan, core fucosylated, FA2 N-glycan, Mannotriose-(fucosyl-di-[N-acetylglucosamine]), bis(N-acetylglucosaminyl)-

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About This Item

Empirical Formula (Hill Notation):
C56H94N4O40
CAS Number:
84825-26-3
Molecular Weight:
1463.35
MDL number:
MFCD01310896
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

Porcine

Quality Level

200

assay

≥90% (HPLC)

form

solid

Storage temp.

−20°C

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Biochem/physiol Actions

NGA2F N-glycan is a fucosylated biantennary oligosaccharide (FBO) that may be found in the Fc region of IgG. In a study of glycans isolated from a recombinant monoclonal IgG1, high-mannose oligosaccharides were reported to be cleared at a faster rate than FBOs. A study of diethylnitrosamine (DENA) induced hepatocellular carcinoma (HCC) in rats found significant elevation levels of two specific N-glycans compared to NGA2F N-glycan levels in HCC rats. NGA2F, NGA2FB, and NA2F N-glycan levels in normal human serum were found to be age- and gender-dependent.

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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