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N3412

Sigma-Aldrich

Monoclonal Anti-Neuropilin-2 antibody produced in mouse

clone 96009, purified immunoglobulin, lyophilized powder

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About This Item

MDL number:
MFCD02097028
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

96009, monoclonal

form

lyophilized powder

species reactivity

rat

technique(s)

indirect ELISA: 0.5-1 μg/mL using rrNeuropilin-2 extracellular domain
western blot: 1-2 μg/mL using rrNeuropilin-2 extracellular domain

isotype

IgG2b

UniProt accession no.

O35276

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Nrp2(81527)

General description

Neuropilin-2 (NRP-2) is expressed in the neurons of the developing nervous system in rats.

Specificity

Shows no cross-reactivity with human neuropilin-1.

Immunogen

purified, NS0-derived, recombinant rat neuropilin-2 extracellular domain.

Biochem/physiol Actions

Neuropilin-2 (NRP-2) is involved in assembly of Schwann cells into aggregates, which have a role in the regeneration of neurons.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
035K1532

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A L Kolodkin et al.
Cell, 90(4), 753-762 (1997-08-22)
The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been shown to function in repulsive axon guidance. Semaphorin III (Sema III) is a secreted protein that in vitro causes neuronal growth cone
J Ara et al.
Journal of neuroscience research, 79(4), 468-475 (2005-01-07)
Neuropilins and group A plexins are components of receptor complexes for class 3 semaphorins, gradients of which help to guide migration of neural progenitor cells and axonal growth cones during development. We demonstrated previously that neuropilins and class 3 semaphorins

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