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Key Documents

M9037

Sigma-Aldrich

MAN-9 Glycan

≥80%

Synonym(s):

(Man)9(GlcNAc)2, Mannonanose-di-(N-acetyl-D-glucosamine)

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About This Item

Empirical Formula (Hill Notation):
C70H118N2O56
CAS Number:
71246-55-4
Molecular Weight:
1883.67
UNSPSC Code:
12352201
PubChem Substance ID:
329818078

biological source

Porcine thyroid

assay

≥80%

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO[C@H]3O[C@H](CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O[C@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]7O)[C@@H]3O)[C@@H](O)[C@H](O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]8O[C@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]9O[C@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]%10O)[C@@H]2O)[C@H](O)[C@H]1NC(C)=O)[C@H](O)CO

InChI

1S/C70H118N2O56/c1-15(83)71-17(3-73)30(86)53(18(85)4-74)121-61-29(72-16(2)84)40(96)54(26(12-82)118-61)122-66-52(108)56(124-69-60(47(103)37(93)24(10-80)116-69)128-70-59(46(102)36(92)25(11-81)117-70)127-65-50(106)43(99)33(89)21(7-77)113-65)39(95)28(120-66)13-109-62-51(107)55(123-68-58(45(101)35(91)23(9-79)115-68)126-64-49(105)42(98)32(88)20(6-76)112-64)38(94)27(119-62)14-110-67-57(44(100)34(90)22(8-78)114-67)125-63-48(104)41(97)31(87)19(5-75)111-63/h3,17-70,74-82,85-108H,4-14H2,1-2H3,(H,71,83)(H,72,84)/t17-,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53+,54+,55-,56-,57-,58-,59-,60-,61-,62-,63+,64+,65+,66-,67-,68+,69+,70+/m0/s1

InChI key

KOZCRMMRHOKBQT-YBLKTATPSA-N

General description

Many of the key molecules involved in the innate and adaptive immune response are glycoproteins [1]

Application

Manno-oligosaccharide derived from N-linked glycoprotein MAN-9 Glycan has been used in a study to assess a new tool for the identification of lectins. [2] It has also been used in a study to investigate glycosylation and the immune system. [1]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCH9932
SLCH7967
SLBZ2861
SLBR9631V
SLBQ5565V

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G Lauc et al.
Glycobiology, 10(4), 357-364 (2000-04-15)
One of the proposed functions for the carbohydrate structures on glycoconjugates is the transfer of information through interaction with specific lectin receptors. However, the number of elucidated functional lectin-carbohydrate interactions is still relatively small, largely due to the lack of
P M Rudd et al.
Science (New York, N.Y.), 291(5512), 2370-2376 (2001-03-28)
Almost all of the key molecules involved in the innate and adaptive immune response are glycoproteins. In the cellular immune system, specific glycoforms are involved in the folding, quality control, and assembly of peptide-loaded major histocompatibility complex (MHC) antigens and

Articles

N-Linked Glycans Overview

N-linked glycosylation, modification, and degradation

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