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M6692

Sigma-Aldrich

Monoclonal Anti-Minor Vault Protein 193 antibody produced in mouse

250 μg/mL, clone p193-4, tissue culture supernatant

Synonym(s):

Anti-VPARP, Anti-p193

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

tissue culture supernatant

antibody product type

primary antibodies

clone

p193-4, monoclonal

species reactivity

human

concentration

250 μg/mL

technique(s)

immunocytochemistry: 1:10-1:20 using 4% paraformaldehyde-fixed cytospin preparation
immunohistochemistry (frozen sections): 1:10-1:20
western blot (chemiluminescent): 1:10-1:20

isotype

IgG1κ

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... PARP4(143)

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General description

Minor vault protein 193 is also known as poly (ADP-ribose) polymerase family member 4 (PARP4). Along with two other proteins, it is part of vaults (ribonucleoprotein particles present in the cytoplasm). The molecular weight of this protein is 193kDa.

Specificity

Reacts with an internal epitope of (aa 491-494, HPGE) of p193.

Immunogen

E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of p193 cDNA.

Biochem/physiol Actions

Minor vault protein 193 is highly expressed in tumors.

Physical form

Supplied in serum-free culture medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

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Storage Class

10 - Combustible liquids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.
Kickhoefer VA
The Journal of Cell Biology, 146(5), 917-928 (1999)
Formate assay in body fluids: application in methanol poisoning.
A B Makar et al.
Biochemical medicine, 13(2), 117-126 (1975-06-01)

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