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M6546

Sigma-Aldrich

(±)-2-(p-Methoxyphenoxy)propionic acid

solid, ≥98%

Synonym(s):

PMP

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About This Item

Empirical Formula (Hill Notation):
C10H12O4
CAS Number:
13794-15-5
Molecular Weight:
196.20
MDL number:
MFCD01310545
UNSPSC Code:
12352202
PubChem Substance ID:
24897095
NACRES:
NA.77
Pricing and availability is not currently available.

Product Name

(±)-2-(p-Methoxyphenoxy)propionic acid, ≥98%

biological source

synthetic (organic)

Quality Level

200

assay

≥98%

form

solid

SMILES string

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

InChI key

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Related Categories

Application

(±)-2-(p-Methoxyphenoxy)propionic acid may be used as a sweet taste receptor antagonist to study its effect on allulose-induced glucagon-like peptide 1 (GLP-1) secretion rats.[1] It may also be used to study the response of the secretin tumor cell line (STC-1) to sweetener in the presence and absence of (±)-2-(p-methoxyphenoxy)propionic acid or lactisole.[2]

Biochem/physiol Actions

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.[3]

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000254525
0000254526
0000279681
0000232599
0000258201

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Li-Chun Chen et al.
Food chemistry, 212, 768-777 (2016-07-05)
The biological functions of cell membranes strongly influence the binding and transport of molecular species. We developed STC-1 cell line stably expressing the sweet taste receptor (T1R2/T1R3), and explored the possible correlation between sweeteners and membrane dipole potential of STC-1
Zhihao Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 1350-1358 (2016-11-03)
Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a prized traditional Chinese Medicine, has been used in China and Southeast Asian countries for centuries. The present study was aimed to investigate the effects and the possible mechanisms of the Dendrobium
Kensuke Ninomiya et al.
The EMBO journal, 39(3), e102729-e102729 (2019-11-30)
A number of long noncoding RNAs (lncRNAs) are induced in response to specific stresses to construct membrane-less nuclear bodies; however, their function remains poorly understood. Here, we report the role of nuclear stress bodies (nSBs) formed on highly repetitive satellite
Lilli Saarinen et al.
PloS one, 12(4), e0174898-e0174898 (2017-04-21)
Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal
Almudena Aguilera-Diaz et al.
PloS one, 15(1), e0227986-e0227986 (2020-01-25)
The diagnosis of myeloid neoplasms (MN) has significantly evolved through the last few decades. Next Generation Sequencing (NGS) is gradually becoming an essential tool to help clinicians with disease management. To this end, most specialized genetic laboratories have implemented NGS
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