Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.
Specificity
Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms. The hemopexin domain is removed from the smallest active form of MMP-23 and the antibody does not detect this form.
Immunogen
synthetic peptide corresponding to the C-terminal of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).
Biochem/physiol Actions
Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.
Physical form
Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Scandinavian journal of immunology, 93(1), e12962-e12962 (2020-08-28)
It has been reported that EMMPRIN is involved in the regulation of immune response and the induction of MMPs production by fibroblasts. The aim of this study was to describe the intestinal gene expression and protein production of EMMPRIN, MMP23
European journal of human genetics : EJHG, 13(2), 139-149 (2004-10-16)
Structural chromosome abnormalities have aided in gene identification for over three decades. Delineation of the deletion sizes and rearrangements allows for phenotype/genotype correlations and ultimately assists in gene identification. In this report, we have delineated the precise rearrangements in four
Matrix metalloproteinases.
H Nagase et al.
The Journal of biological chemistry, 274(31), 21491-21494 (1999-07-27)
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