L8025
Lectin from Maackia amurensis
lyophilized powder
Synonym(s):
Maackia amurensis agglutinin, MAA
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
MDL number:
UNSPSC Code:
12352200
Recommended Products
form
lyophilized powder
potency
<10 μg per mL agglutination activity
composition
Protein, ≥85% Lowry
impurities
salt, essentially free
storage temp.
2-8°C
Biochem/physiol Actions
MAA consists of two molecular species, a strongly hemagglutinating hemagglutinin (MAH) and a strongly mitogenic hemagglutinin (MAL). The mitogenic activity of the latter is inhibited by α-sialyl-[2→3]-lactose. MAA interacts with sialic acid-containing glycoconjugate and may be useful for fractionation of sialylated oligosaccharides.
Preparation Note
Purified by affinity chromatography using a modification of the method of Wang and Cummings.[1]
Analysis Note
Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 7.2 of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of human blood group O erythrocytes after 1 hr incubation at 25 °C.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
W C Wang et al.
The Journal of biological chemistry, 263(10), 4576-4585 (1988-04-05)
We recently reported that the purified leukoagglutinin (designated MAL) from the seeds of the leguminous plant Maackia amurensis is a potent leukoagglutinin for the mouse lymphoma cell line BW5147 (Wang, W.-C., and Cummings, R. D. (1987) Anal. Biochem. 161,80). We
Jhon Alberto Ochoa-Alvarez et al.
PloS one, 7(7), e41845-e41845 (2012-07-31)
Cancer is a leading cause of death of men and women worldwide. Tumor cell motility contributes to metastatic invasion that causes the vast majority of cancer deaths. Extracellular receptors modified by α2,3-sialic acids that promote this motility can serve as
Articles
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
