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L7635
L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean)
≥96%
Synonym(s):
1-Acyl-sn-glycero-3-phospho-(1-D-myo-inositol)
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1 MG
$175.18
5 MG
$836.00
$175.18
List Price$194.00Save 10%Web-Only Promotion
Available to ship onApril 29, 2025Details
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1 MG
$175.18
5 MG
$836.00
About This Item
$175.18
List Price$194.00Save 10%Web-Only Promotion
Available to ship onApril 29, 2025Details
Request a Bulk Order
Recommended Products
biological source
soybean
Quality Level
assay
≥96%
form
powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Application
L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean) has been used as an agonist of G protein-coupled receptor 55 (GPR55).[1]
Biochem/physiol Actions
L-α-Lysophosphatidylinositols (LPI) functions as an endogenous ligand for putative cannabinoid receptor and G protein-coupled receptor 55 (GPR55). LPI plays a regulatory role in cell proliferation, migration and function.[2] Increased circulatory levels of LPI has been observed in the obese patients.[3] In addition, overexpression of LPI leads to the development of various types of cancers including ovarian and breast cancer. LPI can be used as a potential diagnostic and prognostic biomarker for ovarian cancer.[4]
L-α-Lysophosphatidylinositols from Glycine max (soybean) are enriched with stearate and palmitate. Soybean Lysophosphatidylinositols may be compared with other lysophosphatidylinositol for biological activities which depend upon the identity of the acylated fatty acid.
Quality
Contains primarily palmitic and stearic acids.
Preparation Note
Prepared by the action of phospholipase A on L-α-phosphatidylinositol.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The L-alpha-lysophosphatidylinositol/GPR55 system and its potential role in human obesity
Moreno-Navarrete J, et al.
Diabetes, 61(2), 281-291 (2012)
The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55
Sharir H, et al.
Journal of Neuroimmune Pharmacology, 7(4), 856-865 (2012)
Lysophosphatidylinositol stimulates [³⁵S]GTPγS binding in the rat prefrontal cortex and hippocampus.
Maria Luisa Rojo et al.
Neurochemical research, 37(5), 1037-1042 (2012-01-25)
Lysophosphatidylinositol (LPI) is a biologically active lipid that produces a number of responses in cultured cells, and has been suggested to have neuroprotective properties in vivo. Some of the actions of LPI are mediated by G-protein coupled receptors, but it
Lysophosphatidylinositol signalling: New wine from an old bottle.
Pi?eiro R, Falasca M.
Biochimica et Biophysica Acta, 182, 694-705 (2012)
A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signaling pathways in sensory nerves in vivo
Gangadharan V, et al.
Pain, 154(12) (2013)
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What is the molecular weight of L-α-Lysophosphatidylinositol sodium salt from Glycine max, Product L7635?
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We have calculated a value of 605.1, based on the structure of phosphatidyl-1-inositol and the assumption that the main fatty acids present as part of the structure are C16:0 (58%) and C18:0 and C18:2 (42%).
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What fatty acid groups does L-α-Lysophosphatidylinositol sodium salt from Glycine max, Product L7635, contain?
1 answer-
The main fatty acid group is palmitic acid. The next most abundant fatty acid groups tend to be stearic acid and linolenic acid, and then oleic acid and linoleic acid.
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