synthetic peptide corresponding to the N-terminal extracellular domain of human luteinizing hormone/choriogonadotropin receptor, conjugated to KLH. The immunizing peptide has 84% similarity with the mouse.
Biochem/physiol Actions
Luteinizing hormone (LH) is produced by the pituitary gland on stimulation gonadotrophin-releasing hormone secreted by the hypothalamus. LH binds to the LH receptor present on the Leydig cells of testis to stimulate the production of testosterone. In ovary, LH controls the ovulation, maturation of oocytes and gonadal steroidogenesis.
Physical form
Solution in phosphate buffered saline, 0.1% sodium azide.
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