L-leucine-agarose is used in protein chromatography, affinity chromatography and amino acid resins. L-leucine-agarose has been used to study pulp regeneration following pulp exposure as well as to compare polymeric and monomeric affinity ligands′ adsorption affinity, capacity and selectivity to oligopeptide.
Journal of colloid and interface science, 355(2), 478-485 (2011-01-15)
This work aimed to compare two types of affinity ligands, i.e. polymeric and monomeric ligands, by investigating their adsorption affinity, capacity and selectivity to oligopeptide. The peptide NH(2)-VVRGCTWW-COOH (VW-8) was chosen as the target adsorbate, while histidine (His), aspartic acid
Biochemical and biophysical research communications, 396(3), 667-673 (2010-05-05)
An enzyme was purified from the pyloric caecum of tambaqui (Colossoma macropomum) through heat treatment, ammonium sulfate fractionation, Sephadex G-75 and p-aminobenzamidine-agarose affinity chromatography. The enzyme had a molecular mass of 23.9 kDa, NH(2)-terminal amino acid sequence of IVGGYECKAHSQPHVSLNI and
Cell biochemistry and function, 36(8), 431-442 (2018-11-10)
Leucine-rich repeat kinase 2 (LRRK2) is a causal gene of Parkinson disease. G2019S pathogenic mutation increases its kinase activity. LRRK2 regulates various phenotypes including autophagy, neurite outgrowth, and vesicle trafficking. Leucyl-tRNA synthetase (LRS) attaches leucine to tRNALeu and activates mTORC1.
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