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L3776

Sigma-Aldrich

Leukotriene C3

~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH, ≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C30H49N3O9S
CAS Number:
77209-77-9
Molecular Weight:
627.79
MDL number:
MFCD00214089
UNSPSC Code:
12352211
PubChem Substance ID:
24896355

assay

≥97% (HPLC)

concentration

~50 μg/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH

functional group

carboxylic acid

shipped in

dry ice

Storage temp.

−20°C

SMILES string

CCCCCCCC\C=C\C=C\C=C\C(SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(O)CCCC(O)=O

InChI

1S/C30H49N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h9-13,16,22-25,34H,2-8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b10-9+,12-11+,16-13+

Inchi Key

AIJDQMYBRDJHHT-FNBQXVLZSA-N

Packaging

Packaged under argon.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
092H3371

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S E Dahlén et al.
European journal of pharmacology, 86(2), 207-215 (1982-12-24)
Eight biosynthetically formed cysteine-containing leukotrienes dose dependently (0.01-100 nM) contracted parenchymal strips of guinea-pig lung. The response to the leukotrienes was slow in onset, remarkably long-lasting and often tachyphylactic upon repeated administration. All the leukotrienes (LTC3, 8,9-LTC3, LTC4, 11-trans-LTC4, LTC5
Metabolism of leukotriene C3.
S Hammarström
Advances in prostaglandin, thromboxane, and leukotriene research, 9, 83-101 (1982-01-01)
C C Reddy et al.
Archives of biochemistry and biophysics, 279(2), 211-217 (1990-06-01)
Evidence for the formation of a positional isomer of leukotriene (LT) C3 (8,9-LTC3) from dihomo-gamma-linolenic acid has been published (Hammarström, S. J. Biol. Chem. 256, 7712-7714, 1981). This report describes the conversion of dihomo-gamma-linolenic acid to a postulated intermediate in
Biosynthesis and metabolism of leukotrienes.
S Hammarström
Monographs in allergy, 18, 265-271 (1983-01-01)
Rapid in vivo metabolism of leukotriene C3 in the monkey Macaca irus.
S Hammarström et al.
Biochemical and biophysical research communications, 101(4), 1109-1115 (1981-08-31)
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