Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

L2662

Sigma-Aldrich

Lectin from Viscum album (European mistletoe)

lyophilized powder

Synonym(s):

Viscum album agglutinin, VAA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD01777962
UNSPSC Code:
12352200

form

lyophilized powder

potency

<16 μg/mL agglutination activity

composition

Protein, ~50% Lowry

storage temp.

−20°C

Biochem/physiol Actions

VAA is not blood group specific, but has an affinity for terminal β-D-galactosyl residues. VAA inhibits protein synthesis similarly to Ricin (RCA60) and inhibits allergen induced histamine release in vitro from human leukocytes.

Physical form

Highly purified, lyophilized powder containing phosphate buffer salts. Package size based on protein content.

Preparation Note

Purified by affinity chromatography using a modification of the method of Ziska.

Analysis Note

Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of human blood group O erythrocytes after 1 hour incubation at 25 °C.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
100K38061
059H3782
100K3806

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

P Ziska et al.
Experientia, 34(1), 123-124 (1978-01-15)
A lectin from Viscum album which specifically binds to D-galactose was isolated by affinity chromatography on O-lactosyl-, O-galactosyl-polycarylamide or hydrolized sepharose 4 B. Some serological and physicochemical properties of the agglutination are reported.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service