K4889
Anti-Potassium Channel KVβ2 antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-KCNAB2
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, rat, mouse
technique(s)
immunohistochemistry: suitable using mouse brain sections
western blot: 1:200-1:400 using rat brain and Jurkat cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KCNAB2(8514)
mouse ... Kcnab2(16498)
rat ... Kcnab2(29738)
Immunogen
synthetic peptide SPGMIYSTRYGSPKR(C), corresponding to amino acid residues 20-34 of rat KVβ2.
Target description
KVβ2, as well as the other KVβ subunits can bind to all the members of the large KV1.x (Shaker) channel subfamily. However, recent evidence suggests that it can also bind to members of the KV4.x subfamily. KVβ2 is the most abundant β subunit in the brain where it couples with all the KV1.x subunits, but the protein is also expressed in peripheral tissues including heart, lung and cells of hematopoietic origin such as T cells where it couples with KV1.3, the dominant voltage-dependent K+ channel in these cells.
Physical form
Lyophilized powder from phosphate buffered saline (PBS), pH 7.4, containing 1% BSA and 0.25% sodium azide.
Reconstitution
Reconstitute the lyophilized vial with 50μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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