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K4269

Sigma-Aldrich

KAB-18 hydrochloride

≥98% (HPLC), powder

Synonym(s):

Biphenyl-2-carboxylic acid 1-(3-phenyl-propyl)-piperidin-3-ylmethyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C28H31NO2 · HCl
CAS Number:
Molecular Weight:
450.01
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

H2O: ≥9 mg/mL

storage temp.

2-8°C

SMILES string

Cl.O=C(OCC1CCCN(CCCc2ccccc2)C1)c3ccccc3-c4ccccc4

InChI

1S/C28H31NO2.ClH/c30-28(27-18-8-7-17-26(27)25-15-5-2-6-16-25)31-22-24-14-10-20-29(21-24)19-9-13-23-11-3-1-4-12-23;/h1-8,11-12,15-18,24H,9-10,13-14,19-22H2;1H

InChI key

VBAFEOBDSOCKKO-UHFFFAOYSA-N

Biochem/physiol Actions

KAB-18 is a negative allosteric modulator (NAM) at Hα2 β4 nChR nicotinic cholinergic receptors.
KAB-18 is a negative allosteric modulator (NAM) at Hα2 β4 nChR.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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