The gene KIF5C (kinesin family member 5C) belongs to the kinesin superfamily (KIF), the members of which are involved in brain functioning, development, and survival. It encodes the kinesin heavy chain that is a kinesin I motor neuron protein.
Immunogen
synthetic peptide corresponding to amino acid residues 938-957 from human kinesin 5C.
Biochem/physiol Actions
The gene KIF5C (kinesin family member 5C) encodes a kinesin motor that functions in the transport of apical cargo molecules to a post-Golgi endosomal compartment. Mutations in this gene have been associated with malformations of cortical development (MCD) and microcephaly.
Physical form
Solution in phosphate buffered saline containing 1 mg/mL BSA and 0.05% sodium azide.
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Storage Class
10 - Combustible liquids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Journal of medical genetics, 51(7), 487-494 (2014-05-09)
Kinesin superfamily (KIF) genes encode motor proteins that have fundamental roles in brain functioning, development, survival and plasticity by regulating the transport of cargo along microtubules within axons, dendrites and synapses. Mouse knockout studies support these important functions in the
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