I6152
Anti-Interleukin-2 Soluble Receptor α antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-IL-2 sRα
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About This Item
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: suitable
neutralization: suitable
western blot: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IL2RA(3559)
Specificity
The antibody will neutralize human cell surface IL-2 receptor α mediated-bioactivity. The antibody shows ≤15% cross-reactivity with recombinant human IL-2 Rγ, ≤ 5% cross-reactivity with recombinant human IL-6 sR, and ≤1% cross-reactivity with recombinant human IL-1 sRII and IL-2 sRβ.
Immunogen
recombinant human IL-2 soluble receptor α, expressed in Sf 21 insect cells.
Application
Anti-Interleukin-2 Soluble Receptor α antibody may be used in immunoblotting at a working concentration of 0.1-0.2 μg/ml. For flow cytometry, the recommended concentration is 2-3 μg/106 cells. The antibody is suitable for IL-2 sR α neutralization assays.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Sune Skeldal et al.
The Journal of biological chemistry, 287(52), 43798-43809 (2012-10-30)
Neurotrophins comprise a group of neuronal growth factors that are essential for the development and maintenance of the nervous system. However, the immature pro-neurotrophins promote apoptosis by engaging in a complex with sortilin and the p75 neurotrophin receptor (p75(NTR)). To
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