I4895
Anti-Interleukin-9 antibody produced in goat
IgG fraction of antiserum, lyophilized powder
Synonym(s):
Anti-IL-9
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
biological source
goat
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
neutralization: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Il9(16198)
General description
Interleukin-9 (IL-9) is a pleotropic cytokine produced by activated T cells and also by mast cells in response to LPS and IL-1. The production of IL-9 is amplified by TGF-β, IL-2 and IL-25. The biological effects of IL-9 are mediated by IL-9 receptor (IL-9R) that is made up of an α and a γ chain. IL-9 signalling results in the activation of major signalling pathways involving STAT1, -3 and -5, MAPK, PI3K and IRS. IL-9 is a pro-inflammatory cytokine and promotes allergic inflammation and airway remodelling in lungs. It also is important in cell growth and differentiation of T cells, B cells, mast cells, hematopoietic progenitors, epithelial cells and airway smooth muscle cells
Anti-Interleukin-9 recognizes mouse IL-9. It does not neutralize the activity of recombinant human IL-9.
Anti-Interleukin-9 recognizes mouse IL-9. It does not neutralize the activity of recombinant human IL-9.
Specificity
The antibody neutralizes the biological activity of recombinant mouse IL-9, but not recombinant human IL-9.
Immunogen
recombinant mouse IL-9 expressed in Sf 21 insect cells.
Application
Anti-mouse Interleukin-9 antibody may be used for immunoblotting at a working concentration of 1.0 μg/ml. For ELISA a concentration of 0.5 μg/ml is recommended. The antibody is also suitable for neutralization reactions
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline
Preparation Note
Purified using protein G
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
J C Renauld et al.
Journal of leukocyte biology, 57(3), 353-360 (1995-03-01)
Interleukin-9 (IL-9) is a multifunctional cytokine produced by activated TH2 clones in vitro and during TH2-like T cell responses in vivo. The IL-9 receptor is a member of the hemopoietin receptor superfamily and interacts with the gamma chain of the
Ritobrata Goswami et al.
Journal of immunology (Baltimore, Md. : 1950), 186(6), 3283-3288 (2011-03-04)
IL-9 was first described in the late 1980s as a member of a growing number of cytokines that had pleiotropic functions in the immune system. Although many biological functions have been attributed to IL-9, it remains an understudied cytokine. A
Jennifer Kearley et al.
American journal of respiratory and critical care medicine, 183(7), 865-875 (2010-10-26)
IL-9 is a pleiotropic cytokine that has multiple effects on structural as well as numerous hematopoietic cells, which are central to the pathogenesis of asthma. The contribution of IL-9 to asthma pathogenesis has thus far been unclear, due to conflicting
Ulla-Angela Temann et al.
The Journal of clinical investigation, 109(1), 29-39 (2002-01-10)
IL-9 is a pleiotropic cytokine with multiple functions on many cell types involved in the pathology of human asthma. The constitutive overexpression of IL-9 in the lungs of transgenic mice resulted in an asthma-like phenotype. To define the contribution of
J C Renauld et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(12), 5690-5694 (1992-06-15)
Interleukin 9 (IL-9) is a T-cell-derived lymphokine that induces the proliferation of various lymphoid and hemopoietic cells. A cDNA clone encoding the murine IL-9 receptor was isolated by expression cloning in COS cells and screening with 125I-labeled IL-9. Transient expression
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service